Pakistan Journal of Biological Sciences

Volume 25 (11), 978-985, 2022


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Enhancement of Cluster Differentiation Antigen 4 and the Body Mass Index in Patients with HIV

Adius Kusnan, Rahmawati , Indria Hafizah, Haryati , La Rangki, Saida and Mubarak

Background and Objective: The HIV is the virus that can cause AIDS by attacking white blood cells such as T cells CD4+. This study aimed to determine the relationship between antiretroviral (ARV) drugs and supplements of black tea (Camellia sinensis var. assamica) powder to increase the CD4 and Body Mass Index (BMI) in patients with HIV. Materials and Methods: This study used a quasi-experiment. From the average number of 10 patient visits every month in the period of January to March, 2021 in the outpatient clinic for patients diagnosed positive with HIV-AIDS, seventy patients were enlisted and divided into 2 groups from 12 districts, 35 groups intervention received ARV drugs and supplements steeping black tea powder form as much as 1,505 mg, equivalent to 5-7 glasses a 1,000-1,400 mL/day for 24 weeks, while the control group of patients received ARV drugs, standard diet each house and nutrition education. Results: This study showed a BMI before the intervention control group’s 1st week 19.31±2.17 and after the intervention for 24 weeks, a BMI of 18.78±2.42. CD4 levels before the intervention, the 1st week were 380.57±78.63 and after the intervention for 24 weeks, 365.74±81.13 in this case either BMI or CD4 did not experience significant improvements. While the intervention group before the intervention 1st week BMI was 21.61±3.32 and after the intervention for 24 weeks, 22.2±3.19 or increased significantly (p = 0.002) and the levels of CD4 in the 1st week before the intervention, 360.91±221.20 and after the intervention for 24 weeks, 425.14±178.87 or increased significantly (p = 0.003). Conclusion: The ARV therapy and black tea powder significantly increased levels of CD4 and BMI HIV sufferers through the improvement of the status of T-cell immunity and body mass index.

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How to cite this article:

Adius Kusnan, Rahmawati , Indria Hafizah, Haryati , La Rangki, Saida and Mubarak, 2022. Enhancement of Cluster Differentiation Antigen 4 and the Body Mass Index in Patients with HIV. Pakistan Journal of Biological Sciences, 25: 978-985.


DOI: 10.3923/pjbs.2022.978.985
URL: https://ansinet.com/abstract.php?doi=pjbs.2022.978.985

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