Flexible Ureteroscopic Holmium Laser Lithotripsy vs Percutaneous Nephrolithotomy for Renal Stones

Dapeng Zong and Pengfei Shao

Background and Objective: The incidence of kidney stones has been increasing in recent years. Percutaneous nephrolithotomy and flexible ureteroscopic holmium laser lithotripsy are common lithotripsy procedures. This study aimed to analyze the differences in the effects of flexible ureteroscopic holmium laser lithotripsy and percutaneous nephrolithotomy for the treatment of kidney stones, as a way to explore the best treatment plan. Materials and Methods: Clinical data of 95 patients with kidney stones admitted to our hospital from May, 2020 to September, 2022 were retrospectively selected and divided into two groups according to different treatment methods, 45 cases in the control group and 50 cases in the study group. The control group underwent percutaneous nephrolithotomy and the study group received flexible ureteroscopic holmium laser lithotripsy and the differences in indexes between the two groups after applying different surgical treatments were compared. Results: The study group had longer operation time, less intraoperative bleeding, shorter length of stay and higher treatment cost than the control group (p<0.05). After surgery, the CRP, IL-6, WBC counts, BUN, Scr and CysC in the study group were lower compared with the control group (p<0.05). After surgery, the GQOLI-74 scores in the study group were higher compared with the control group (p<0.05), but no significant difference was observed in the IIEF -5 and CIPE scores between two groups (p>0.05). Conclusion: Flexible ureteroscopic holmium laser lithotripsy and holmium laser lithotripsy with percutaneous nephrolithoscopy are both effective in kidney stone extraction, but holmium laser lithotripsy with flexible ureterorenoscopy has the advantages of less trauma, faster recovery and higher safety, but the treatment cost is relatively high and the appropriate procedure can be determined according to the actual condition of patients.

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