Background and Objective: Malnutrition has become a health problem in developing countries such as Indonesia. This can provide an effect on body composition, decreasing albumin levels and immunity status. Patin fish is well-known to have a high level of protein concentration and has a positive-effect on malnutrition. To investigate the effect of Patin fish protein concentrate (PFPC) on the albumin levels and immunity status of Sprague Dawley baby rat’s malnutrition. Materials and Methods: The study was a true-experiment study with a randomized pre-posttest with a control group. Thirty rats were divided into 5 groups; control of normal (K1) and malnutrition (K2), malnutrition with PFPC 13.26 (P1), 19.89 (P2) and casein 13.26 (P3) mg g1 b.wt. day1. The analysis was carried out with the paired t-test, Wilcoxon, ANOVA and Kruskal Wallis test. Results: The results showed that malnutrition has an effect on BW, albumin levels, leukocytes count and IgG levels. Post-intervention showed an increase of albumin levels in the intervention groups (p<0.05) and a significant decrease in control groups (p<0.05). There is a decrease in leukocytes count and IgG level post-intervention in intervention groups (p<0.05) and a significant increase in the post-intervention control groups (p<0.05). There were significant differences between all groups on albumin levels, leukocytes count and IgG levels. Conclusion: PFPC could improve albumin and immunity levels in malnutrition baby rats. PFPC dose of 19.89 mg g1 b.wt. day1 is the best formula in improving albumin and immunity levels.
Samnil Astuti Fitri, Annisa Zikra, Muflihatul Muniroh and Tri Winarni Agustini, 2021. Patin (Pangasianodon hypophthalmus) Fish Protein Concentrate Improves Albumin and Immunity Levels in Malnutrition Rats. Asian Journal of Clinical Nutrition, 13: 1-8.